Cardiff City's Isaak Davies, Jamilu Collins and Kion Etete are all set for lengthy spells on the sidelines due to injury.
The trio missed the Bluebirds' 2-0 pre-season win over Bristol Rovers at the Memorial Ground.
And boss Erol Bulut confirmed Wales Under-21 international Davies, Nigerian left-back Collins and forward Etete will miss the beginning of Cardiff's 2024-25 season.
"Kion is injured, Isaak is injured and JC is also injured from the last game in Austria against Hertha," Bulut told BBC Sport Wales.
"It looks like Isaak Davies will be out for four months, Kion will be out for three months, and with JC, six to eight weeks.
"These were the negative things, but football is like this."
Callum Robinson, David Turnbull and Mark McGuinness also missed the clash with League One outfit Rovers.
Robinson and Turnbull were rested having played the entirety of the 2-1 win against Reading at Cardiff City Stadium three days earlier.
And Bulut confirmed defender McGuinness was omitted from the squad as a precautionary measure due to a muscle complaint.
"We protected him today because he was feeling a muscular problem," Bulut said on McGuinness.
Aaron Ramsey and Joe Ralls struck in either half as the Bluebirds defeated League One Bristol Rovers in their final pre-season fixture.
Cardiff begin their 2024-25 Championship campaign against Sunderland in south Wales on 10 August (12:30 BST).