Ledley was the only City player on duty and he was subbed after 49 minutes.
There was no place in the matchday squad for Aaron Ramsey or Darcy Blake.
Next up Wales face Holland in Rotterdam on Sunday.
Tonight it's Steve McPhail's chance for a cap as the Reublic of Ireland face Columbia at Craven Cottage. McPhail has not been named in the starting XI so will be hoping for a place on the bench.
On Friday night Kevin McNaughton and Gavin Rae are in the Scotland squad as they face the Czech Republic in Prague.