James Collins is likely to start for the Welsh lads while Danny Brimble, Michael Parkins, Stuart Fleetwood, Danny Thomas and Nicky Fish are also in the squad.
A 7th player Byron Anthony is ruled out through injury.
Of the City players Collins is the most experienced with several league starts for the first team this season. Sturat Fleetwood has been on the bench a couple of times and has twice played small parts in the Carling Cup and the league.
The other lads are regular City reserve team players.
The game against the old enemy is live on Sky Sports 1 tonight, ko 7:15pm.
England include the Premierships youngest scorer, James Milner of Leeds and also Gary O'Neil who scored a couple of goals for Pompey last week in their demolition of Leeds Utd at Fratton Park.