They will be as follows:
Arsenal v Leeds United
Saturday 8 January 2011
12.45pm kick-off
Live on ITV1
Stevenage v Newcastle United
Saturday 8 January 2011
5.30pm kick-off
Live on ESPN
Manchester United v Liverpool
Sunday 9 January 2011
1.30pm kick-off
Live on ITV1
Leicester City v Manchester City
Sunday 9 January 2011
4pm kick-off
Live on ESPN
ESPN have one more choice to make but with another seven Premier League teams playing away to lower league opposition it's likely to be one of those.
Last season S4C covered Cardiff's matches against Bristol City and Chelsea live. There's been no announcement from the Welsh broadcaster yet.