The teams met in 2006 when City were the last side to face Arsenal in the FA Cup at Highbury before the Gunners moved to their new stadium.
Cardiff, ball No. 11 were drawn out by Dave Beasent with Roberto Di Mateo drawing out ball No. 35. Arsenal.
It's a plum tie and will guarantee a sell out crowd against major opposition for Ninian Park before the turnstiles stop revolving later in the year.
No ticket details, exact fixture date or news of possible TV coverage has been released yet. Please don't bombard the ticket office for this information. It will be released as soon as possible.
The full draw for the FA Cup 4th round is:
Liverpool v Everton
Manchester United v Tottenham Hotspur
Hull City/Newcastle United v Millwall/Crewe Alexandra
Sunderland v Blyth Spartans/Blackburn Rovers
Hartlepool United v West Ham United
Leyton Orient/Sheffield United v Charlton Athletic/Norwich City
Cardiff City v Arsenal
Portsmouth/Bristol City v Histon/Swansea City
Chelsea/Southend United v Ipswich Town
Cheltenham Town/Doncaster Rovers v Aston Villa
West Bromwich Albion/Peterborough United v QPR/Burnley
Torquay United v Coventry City
Kettering Town v Fulham
Watford v Leicester City/Crystal Palace
Derby County v Nottingham Forest
Birmingham City/Wolverhampton Wanderers v Middlesbrough
Matches to be played on the weekend of January 24th.