Blake will therefore miss the Carling Cup tie when Cardiff face Burton Albion on the same evening.
City will also be without David Marshall who is away on Scotland duty but the Bluebirds will be boosted by the registration of Tom Heaton meaning the club can field a regular goalkeeper against the League 2 side.
Wales face Luxembourg in Llanelli at the same time as Cardiff play Burton. A situatuion that doesn't impress Dave Jones.
Blake will join former Bluebirds Rob Earnshaw, Chris Gunter and Joe Ledley in the Wales camp. James Collins and Aaron Ramsey are injured.